Chromatin Publications

Hwang, W., Venkatasubrahmanyam, S., Ianculescu, A.G., Tong, A., Boone, C., Madhani, H.D. (2003) A conserved RING finger protein required for histone H2B monoubiquitination and cell size control. Molecular Cell 11: 261-266. Published online Dec. 28, 2002. [PDF]

Meneghini, M.D., Wu., M, and Madhani, H.D. (2003) Conserved histone variant H2A.Z prevents the ectopic spread of silent heterochromatin. Cell 112: 725-736. [PDF]

Kobor, M.S., Venkatasubrahmanyam, S., Meneghini, M.D., Gin, J.W., Jennings, J.L., Link, A.J., Madhani, H.D.*, Rine, J.* (2004) A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin. PLoS Biology 2: 587-599. *co-corresponding authors. [PDF]

Raisner, R.M., Hartley, P.D., Meneghini, M.D., Bao, M.Z., Liu, C.L., Schreiber, S.L., Rando, O.J., Madhani, H.D. (2005) Histone variant H2A.Z marks the 5’ ends of both active and inactive genes in euchromatin. Cell 123: 233-248. [PDF]

Raisner, R.M. and Madhani, H.D. (2006) Patterning chromatin: form and function of H2A.Z variant nucleosomes. Current Opinions in Genetics and Development 16: 119-124. [PDF]

Tompa, R., Madhani, H.D. (2007). Histone H3 Lysine 36 Methylation Antagonizes Silencing in Saccharomyces cerevisiae Independently of the Rpd3S Histone Deacetylase Complex. Genetics 175: 585-93. [PDF]

Venkatasubrahmanyam, S., Hwang, W.W. Meneghini, M.D., Tong, A.H. & Madhani, H.D. (2007). Genome-wide, as opposed to local, antisilencing is mediated redundantly by the euchromatic factors Set1 and H2A.Z. Proceedings of the National Academy of Sciences, USA 104: 16609-16614. [PDF]

Raisner, R.M. & Madhani, H.D. (2008). Genomewide screen for negative regulators of sirtuin activity in S. cerevisiae reveals 40 loci and links to metabolism. Genetics 179: 1933-1944. [PDF]

Rougemaille, M., Shankar, S., Braun, S., Rowley, M. & Madhani, H.D. (2008). Ers1, a rapidly diverging protein essential for RNA interference-dependent heterochromatic silencing in Schizosaccharomyces pombe. Journal of Biological Chemistry. 283: 25770-25773. [PDF]

Breslow, D.K., Cameron, D.M., Collins, S.R., Schuldiner, M., Stewart-Ornstein, J., Newman, H.W., Braun, S., Madhani, H.D., Krogan, N.J. & Weissman, J.S. (2008). A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nature Methods 5: 711-718. [PDF]

Hartley, P.D. & Madhani, H.D. (2009). Mechanisms that specify nucleosome location and identity Cell 137: 445-458. [PDF]

Hwang, W.W. & Madhani, H.D. (2009). Nonredundant Requirement for Multiple Histone Modifications for the Early Anaphase Release of the Mitotic Exit Regulator Cdc14 from Nucleolar Chromatin. PLoS Genetics 5:e1000588. [PDF]

Garcia J.F., Dumesic P.A., Hartley P.D., El-Samad H., Madhani H.D. (2010) Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions. Genes and Development 15:1758-71. [PDF]

Braun, S., Garcia, J.F., Rowley, M., Rougemaille, M., Shankar, S., Madhani, H.D. (2011) The Cul4-Ddb1Cdt2 ubiquitin ligase inhibits the invasion of a boundary-associated anti-silencing factor into heterochromatin. Cell 144: 41-54. [PDF]

signaling publications
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